Which of the following is least likely to exacerbate acne?

Choosing to focus on the consumption of alcohol, particularly 3-5 glasses of wine a week, highlights why this option is considered the least likely to exacerbate acne compared to the others. While excessive alcohol consumption can have various negative effects on skin health, moderate wine intake has not been strongly linked to acne development in most studies.

On the other hand, fabric softeners may contain chemicals or fragrances that can irritate the skin, potentially worsening acne. Foods high in table salt can lead to dehydration and increased inflammation, potentially aggravating acne. Working the night shift can disrupt normal sleep patterns, which may impact hormone levels and stress responses, both of which are factors that can negatively influence acne severity.

Thus, drinking wine in moderation is generally not associated with an increase in acne flare-ups, making it the least likely factor to exacerbate the condition.