Is retention hyperkeratosis the only true cause of acne?

Retention hyperkeratosis refers to the accumulation of dead skin cells in the hair follicle, leading to blockages that can cause acne lesions. While it is a significant factor in the development of acne, it is not the sole cause. Acne is a multifactorial skin condition that involves various contributing factors beyond just retention hyperkeratosis.

These factors include increased sebum production, hormonal fluctuations, bacterial growth (particularly Propionibacterium acnes), and inflammation. The interplay of these factors creates an environment conducive to the formation of acne. Thus, stating that retention hyperkeratosis is the only true cause oversimplifies the complexity of acne pathophysiology. Understanding that multiple elements contribute to acne can guide more effective treatment strategies and holistic approaches to skin care.